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Merck

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Muscimol hydrobromide, ≥98% (HPLC), solid,
Especie
human
Isoguvacine hydrochloride, solid,
Especie
human
γ-Aminobutyric acid, ≥99%,
Especie
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human
Propofol, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Ganaxolone, ≥98% (HPLC), solid,
Especie
human, mouse
2,6-Diisopropylphenol, 97%,
Especie
human
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Picrotoxin, powder,
Especie
human
Pregnenolone sulfate sodium salt, ,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human
Ganaxolone, ≥98% (HPLC), solid,
Especie
human, mouse
2,6-Diisopropylphenol, 97%,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GABA A Receptor α 5 Antibody, Chemicon®, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
NO-711 hydrochloride, ≥98% (HPLC),
Especie
human
2,6-Diisopropylphenol, 97%,
Especie
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
L-655,708, ≥98% (HPLC), powder,
Especie
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRA5,
Especie
human