GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
Sinónimos:
Especie:
Human GABRA4 (2557), Mouse Gabra4 (14397), Rat Gabra4 (140675), chicken GABRA4 (422770), cow GABRA4 (282238), dog GABRA4 (482132), sheep GABRA4 (101121776), domestic cat GABRA4 (101098052), domestic guinea pig Gabra4 (100721252), naked mole-rat Gabra4 (101718327)
ID UniProtKB:
ID del gen:
- Human(2557) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
- Mouse(14397) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
- Rat(140675) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- chicken(422770) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- cow(282238) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- dog(482132) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- sheep(101121776) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic cat(101098052) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic guinea pig(100721252) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- naked mole-rat(101718327) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- Domestic Rabbit(100339882) gamma-aminobutyric acid (GABA) A receptor, alpha 4
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
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Descripción
Especie
Small Molecule - Antagonist
Antibodies
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Reactividad de especies
Aplicación
Anticuerpo anti-receptor α4 del GABA A , CT, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
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Especie