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FGFR1OP

FGFR1 oncogene partner

Sinónimos:
FOP
Especie:
ID UniProtKB:
ID del gen:
  • Human(11116) Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  • Mouse(75296) Fgfr1 oncogene partner
  • Rat(365103) FGFR1 oncogene partner
  • sheep(101115039) FGFR1 oncogene partner
  • domestic cat(101099885) FGFR1 oncogene partner
  • dog(612453) FGFR1 oncogene partner
  • Zebrafish(415215) FGFR1 oncogene partner
  • chicken(421568) FGFR1 oncogene partner
  • domestic guinea pig(100728960) FGFR1 oncogene partner
  • cow(506246) FGFR1 oncogene partner
  • naked mole-rat(101707272) FGFR1 oncogene partner

Custom & Knockdown Gene Products

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esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human FGFR1OP,
Especie
human
MISSION® esiRNA, targeting mouse Fgfr1op,
Especie
mouse