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Merck

FGA

fibrinogen alpha chain

Sinónimos:
Fib2
Especie:
ID UniProtKB:
ID del gen:
  • Human(2243) Summary: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
  • Mouse(14161) fibrinogen alpha chain
  • Rat(361969) fibrinogen alpha chain
  • chicken(396307) fibrinogen alpha chain
  • Zebrafish(378986) fibrinogen alpha chain
  • cow(522039) fibrinogen alpha chain
  • Horse(100069763) fibrinogen alpha chain
  • domestic cat(101092934) fibrinogen alpha chain
  • dog(475473) fibrinogen alpha chain
  • naked mole-rat(101697611) fibrinogen alpha chain
  • domestic guinea pig(100720646) fibrinogen alpha chain
  • Domestic Rabbit(100353616) fibrinogen alpha chain
  • sheep(101102090) fibrinogen alpha chain

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Fibrinogen alpha chain (FGA) antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
Fibrinopeptide A human, ≥96% (HPLC),
Especie
human
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human FGA (1),
Especie
human
MISSION® esiRNA, targeting human FGA (3),
Especie
human
MISSION® esiRNA, targeting mouse Fga,
Especie
mouse
MISSION® esiRNA, targeting human FGA (2),
Especie
human
MISSION® esiRNA, targeting human FGA (4),
Especie
human