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Merck

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

Sinónimos:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
  • Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Autotaxin Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, canine, human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-Autotaxin (ENPP2) Antibody, clone 7A5, clone 7A5, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ENPP2,
Especie
human
MISSION® esiRNA, targeting mouse Enpp2,
Especie
mouse