EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
Sinónimos:
EIF2AK1, PKR, PRKR
Especie:
Human EIF2AK2 (5610), Mouse Eif2ak2 (19106), Rat Eif2ak2 (54287), Zebrafish eif2ak2 (100001092), domestic guinea pig Eif2ak2 (100717384), Domestic Rabbit EIF2AK2 (100009013), domestic cat EIF2AK2 (101082744), sheep EIF2AK2 (101121673), dog EIF2AK2 (611397), naked mole-rat Eif2ak2 (101724844) ...Más
ID UniProtKB:
ID del gen:
- Human(5610) Summary: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(19106) eukaryotic translation initiation factor 2-alpha kinase 2
- Rat(54287) eukaryotic translation initiation factor 2-alpha kinase 2
- Zebrafish(100001092) eukaryotic translation initiation factor 2-alpha kinase 2
- domestic guinea pig(100717384) eukaryotic translation initiation factor 2-alpha kinase 2
- Domestic Rabbit(100009013) eukaryotic translation initiation factor 2-alpha kinase 2
- domestic cat(101082744) eukaryotic translation initiation factor 2-alpha kinase 2
- sheep(101121673) eukaryotic translation initiation factor 2-alpha kinase 2
- dog(611397) eukaryotic translation initiation factor 2-alpha kinase 2
- naked mole-rat(101724844) eukaryotic translation initiation factor 2-alpha kinase 2
- Horse(100147679) eukaryotic translation initiation factor 2-alpha kinase 2
- chicken(395147) eukaryotic translation initiation factor 2-alpha kinase 2
- cow(347700) eukaryotic translation initiation factor 2-alpha kinase 2
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Phospho-PKR/EIF2AK2-T446 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-PKR Antibody, clone 2H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, rat
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-PKR (Thr446) Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-PKR/EIF2AK2 Antibody, clone 5B7B6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
PhosphoDetect Anti-PKR (pThr⁴⁵¹) Rabbit pAb, liquid, Calbiochem®,
Reactividad de especies
human, mouse
Aplicación