DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
Sinónimos:
ICF, ICF1, M.HsaIIIB
Especie:
Human DNMT3B (1789), Mouse Dnmt3b (13436), Rat Dnmt3b (444985), domestic guinea pig Dnmt3b (100731772), naked mole-rat Dnmt3b (101725788), dog DNMT3B (100685634), Horse DNMT3B (100053900), domestic cat DNMT3B (101092926), cow DNMT3B (353354), Domestic Rabbit DNMT3B (100349823) ...Más
ID UniProtKB:
ID del gen:
- Human(1789) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
- Mouse(13436) DNA methyltransferase 3B
- Rat(444985) DNA (cytosine-5-)-methyltransferase 3 beta
- domestic guinea pig(100731772) DNA (cytosine-5-)-methyltransferase 3 beta
- naked mole-rat(101725788) DNA (cytosine-5-)-methyltransferase 3 beta
- dog(100685634) DNA (cytosine-5-)-methyltransferase 3 beta
- Horse(100053900) DNA (cytosine-5-)-methyltransferase 3 beta
- domestic cat(101092926) DNA (cytosine-5-)-methyltransferase 3 beta
- cow(353354) DNA (cytosine-5-)-methyltransferase 3 beta
- Domestic Rabbit(100349823) DNA (cytosine-5-)-methyltransferase 3 beta
- sheep(100500777) DNA (cytosine-5-)-methyltransferase 3 beta
- Zebrafish(321084) DNA (cytosine-5-)-methyltransferase 3 beta
- chicken(419287) DNA (cytosine-5-)-methyltransferase 3 beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Dnmt3b Antibody, clone D3B2-2C1, clone D3B2-2C1, from rat,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-DNMT3B Antibody, clone 2N12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Número de producto
Descripción
Especie
esiRNA
Número de producto
Descripción
Especie