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Merck

DIABLO

diablo, IAP-binding mitochondrial protein

Sinónimos:
DFNA64, SMAC
Especie:
Human DIABLO (56616), Mouse Diablo (66593), Rat Diablo (288753), chicken DIABLO (416860), cow DIABLO (493999), domestic guinea pig Diablo (100724526), naked mole-rat Diablo (101708166), sheep DIABLO (101121971), dog DIABLO (477463)
ID UniProtKB:
Q9NR28, B2RDQ0, Q6W3F3, Q96LV0, Q9BT11, Q9HAV6
ID del gen:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
SAB5701661
Anti-Smac/Diablo antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
ZRB2891
Anti-Smac/DIABLO Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry
western blot
AB3609
Anti-Smac/Diablo Antibody, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
EHU145751
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Especie
human
EMU067981
MISSION® esiRNA, targeting mouse Diablo,
Especie
mouse