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Merck

CST3

cystatin C

Sinónimos:
ARMD11
Especie:
Human CST3 (1471), Mouse Cst3 (13010), Rat Cst3 (25307), cow CST3 (281102), sheep CST3 (101104079), domestic cat CST3 (100462660), chicken CST3 (396497), Zebrafish cst3 (791878), Domestic Rabbit CST3 (100009450)
ID UniProtKB:
P01034, B2R5J9, D3DW42, Q6FGW9
ID del gen:
  • Human(1471) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq, Jul 2008]
  • Mouse(13010) cystatin C
  • Rat(25307) cystatin C
  • cow(281102) cystatin C
  • sheep(101104079) cystatin C
  • domestic cat(100462660) cystatin C
  • chicken(396497) cystatin C
  • Zebrafish(791878) cystatin C (amyloid angiopathy and cerebral hemorrhage)
  • Domestic Rabbit(100009450) cystatin C

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB5702889
Anti-Cystatin C Antibody, clone 0Z4G3, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
MSST0060
SILu™Lite CST3, Cystatin C human, recombinant, expressed in E. coli, MS Protein Standard,
Especie
human
MSST0059
SILu™Prot CST3, Cystatin C human, recombinant, expressed in E. coli, SIL MS Protein Standard, 15N-labeled,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU019031
MISSION® esiRNA, targeting human CST3,
Especie
human
EMU082771
MISSION® esiRNA, targeting mouse Cst3,
Especie
mouse