CSF1R
colony stimulating factor 1 receptor
Sinónimos:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Especie:
Human CSF1R (1436), Mouse Csf1r (12978), Rat Csf1r (307403), domestic guinea pig Csf1r (100726053), naked mole-rat Csf1r (101719513), sheep CSF1R (101109969), cow CSF1R (509418), domestic cat CSF1R (493706), Horse CSF1R (100060422), dog CSF1R (489188)
ID UniProtKB:
ID del gen:
- Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
- Mouse(12978) colony stimulating factor 1 receptor
- Rat(307403) colony stimulating factor 1 receptor
- domestic guinea pig(100726053) colony stimulating factor 1 receptor
- naked mole-rat(101719513) colony stimulating factor 1 receptor
- sheep(101109969) colony stimulating factor 1 receptor
- cow(509418) colony stimulating factor 1 receptor
- domestic cat(493706) colony stimulating factor 1 receptor
- Horse(100060422) colony stimulating factor 1 receptor
- dog(489188) colony stimulating factor 1 receptor
- chicken(396406) colony stimulating factor 1 receptor
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CSF-1R/CD115 Antibody clone FER216, clone FER216, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-CD115 (c-fms) Antibody (mouse), PE, clone AFS98, clone AFS98, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
western blot
western blot
Anti-CSF1R/c-FMS Antibody, clone AFS98, ,
Reactividad de especies
mouse
Aplicación
flow cytometry
Anti-CD115 (c-fms) Antibody (mouse), PE, clone AFS98, clone AFS98, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
western blot
western blot
Anti-CSF-1R/CD115 Antibody, clone 1F6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human