COPS6
COP9 signalosome subunit 6
Sinónimos:
CSN6, MOV34-34KD
Especie:
Human COPS6 (10980), Mouse Cops6 (26893), Rat Cops6 (304343), domestic cat COPS6 (101088133), Zebrafish cops6 (550465), domestic guinea pig Cops6 (100719508), naked mole-rat Cops6 (101724377), cow COPS6 (512756), sheep COPS6 (101108276), dog COPS6 (479738)
ID UniProtKB:
ID del gen:
- Human(10980) Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
- Mouse(26893) COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)
- Rat(304343) COP9 signalosome subunit 6
- domestic cat(101088133) COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
- Zebrafish(550465) COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
- domestic guinea pig(100719508) COP9 signalosome subunit 6
- naked mole-rat(101724377) COP9 signalosome subunit 6
- cow(512756) COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
- sheep(101108276) COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
- dog(479738) COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
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