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Merck

CHRM1

cholinergic receptor, muscarinic 1

Sinónimos:
HM1, M1, M1R
Especie:
Human CHRM1 (1128), Mouse Chrm1 (12669), Rat Chrm1 (25229), domestic guinea pig Chrm1 (100728041), domestic cat CHRM1 (493664), domestic cat CHRM1 (101093801), dog CHRM1 (483776), sheep CHRM1 (101117029), cow CHRM1 (281684), Horse CHRM1 (100064117)
ID UniProtKB:
P11229
ID del gen:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
1538902
Pilocarpine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
PHL80370
Pilocarpine hydrochloride, phyproof® Reference Substance,
Especie
human
PHR1493
Pilocarpine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
P0597
Pilocarpine nitrate, meets USP testing specifications,
Especie
human
PHR1494
Pilocarpine Nitrate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
197602
Quinuclidine, 97%,
Especie
rat
1610001
Scopolamine hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
P7412
Pirenzepine dihydrochloride, ≥98% (TLC), powder,
Especie
human
SML0847
Benztropine mesylate, ≥98% (HPLC),
Especie
human
P3794
Procyclidine hydrochloride, ,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
AB5164
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
51330
Harmaline, ≥95%,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
A138
Aminobenztropine, solid,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
HTS044M
Preparación de Membranas ChemiScreen Receptor recombinante muscarínico M1 humano de acetilcolina, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU009821
MISSION® esiRNA, targeting human CHRM1,
Especie
human