CHMP4A
charged multivesicular body protein 4A
C14orf123, CHMP4, CHMP4B, HSPC134, SHAX2, SNF7, SNF7-1, VPS32-1, VPS32A
Human CHMP4A (29082), domestic cat CHMP4A (101080716), dog CHMP4A (480263), cow CHMP4A (613647), sheep CHMP4A (101119907)
- Human(29082) Summary: CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]
- domestic cat(101080716) charged multivesicular body protein 4A
- dog(480263) charged multivesicular body protein 4A
- cow(613647) charged multivesicular body protein 4A
- sheep(101119907) charged multivesicular body protein 4A
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