CENPB
centromere protein B, 80kDa
Sinónimos:
Especie:
Human CENPB (1059), Mouse Cenpb (12616), Rat Cenpb (362217), dog CENPB (485791), domestic cat CENPB (101093012), cow CENPB (788381), cow CENPB (281680), naked mole-rat Cenpb (101700720), domestic guinea pig Cenpb (100713491), sheep CENPB (101110697)
ID UniProtKB:
ID del gen:
- Human(1059) Summary: This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
- Mouse(12616) centromere protein B
- Rat(362217) centromere protein B
- dog(485791) centromere protein B, 80kDa
- domestic cat(101093012) centromere protein B, 80kDa
- cow(788381) centromere protein B, 80kDa
- cow(281680) centromere protein B, 80kDa
- naked mole-rat(101700720) centromere protein B, 80kDa
- domestic guinea pig(100713491) centromere protein B, 80kDa
- sheep(101110697) centromere protein B, 80kDa
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CENP-B Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
esiRNA
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Descripción
Especie