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Merck

CDH5

cadherin 5, type 2 (vascular endothelium)

Sinónimos:
7B4, CD144
Especie:
ID UniProtKB:
ID del gen:
  • Human(1003) Summary: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(12562) cadherin 5
  • Rat(307618) cadherin 5
  • naked mole-rat(101706580) cadherin 5, type 2 (vascular endothelium)
  • domestic guinea pig(100727685) cadherin 5, type 2 (vascular endothelium)
  • sheep(101107462) cadherin 5, type 2 (vascular endothelium)
  • Domestic Rabbit(100301529) cadherin 5, type 2 (vascular endothelium)
  • chicken(374068) cadherin 5, type 2 (vascular endothelium)
  • domestic cat(101084501) cadherin 5, type 2 (vascular endothelium)
  • cow(414735) cadherin 5, type 2 (vascular endothelium)
  • dog(489775) cadherin 5, type 2 (vascular endothelium)
  • Zebrafish(445471) cadherin 5

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-VE-caderina, clon BV6, clone BV6, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anticuerpo anti-VE-cadherina (CD144), clon BV9, clone BV9, from mouse,
Reactividad de especies
human
Aplicación
activity assay
immunocytochemistry
Anti-phospho-VE-Cadherin (Tyr685) Antibody, Alexa Fluor 555 Conjugate, from rabbit, ALEXA FLUOR 555,
Reactividad de especies
bovine, human, porcine
Aplicación
immunocytochemistry
Anti-phospho-VE-cadherin (Tyr731), from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
inhibition assay
western blot
Anti-CDH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CDH5,
Especie
human
MISSION® esiRNA, targeting mouse Cdh5,
Especie
mouse