CDH1
cadherin 1, type 1, E-cadherin (epithelial)
Sinónimos:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Especie:
Human CDH1 (999), Mouse Cdh1 (12550), Rat Cdh1 (83502), dog CDH1 (442858), chicken CDH1 (415860), sheep CDH1 (100294601), domestic guinea pig Cdh1 (100726210), domestic cat CDH1 (101095391), sheep CDH1 (101119747), naked mole-rat Cdh1 (101719565) ...Más
ID UniProtKB:
ID del gen:
- Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
- Mouse(12550) cadherin 1
- Rat(83502) cadherin 1
- dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
- chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
- domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
- domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
- naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
- Zebrafish(114424) cadherin 1, epithelial
- cow(282637) cadherin 1, type 1, E-cadherin (epithelial)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-E-Cadherin Antibody, serum, Upstate®,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide & Ascites Free, clone 67A4, 0.5 mg/mL, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
inhibition assay
western blot
immunofluorescence
inhibition assay
western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
immunofluorescence
Anti-E-Cadherin Antibody, clone 67A4, clone 67A4, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie