CCDC50
coiled-coil domain containing 50
Sinónimos:
C3orf6, DFNA44, YMER
Especie:
Human CCDC50 (152137), Mouse Ccdc50 (67501), Rat Ccdc50 (288022), chicken CCDC50 (424906), sheep CCDC50 (101104368), dog CCDC50 (478675), cow CCDC50 (529404), naked mole-rat Ccdc50 (101704004), domestic guinea pig Ccdc50 (100715264), domestic cat CCDC50 (101080475)
ID UniProtKB:
ID del gen:
- Human(152137) Summary: This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
- Mouse(67501) coiled-coil domain containing 50
- Rat(288022) coiled-coil domain containing 50
- chicken(424906) coiled-coil domain containing 50
- sheep(101104368) coiled-coil domain containing 50
- dog(478675) coiled-coil domain containing 50
- cow(529404) coiled-coil domain containing 50
- naked mole-rat(101704004) coiled-coil domain containing 50
- domestic guinea pig(100715264) coiled-coil domain containing 50
- domestic cat(101080475) coiled-coil domain containing 50
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