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Merck

CASP7

caspase 7, apoptosis-related cysteine peptidase

Sinónimos:
CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Especie:
ID UniProtKB:
ID del gen:
  • Human(840) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(12369) caspase 7
  • Rat(64026) caspase 7
  • Goat(100861343) caspase 7, apoptosis-related cysteine peptidase
  • dog(486896) caspase 7, apoptosis-related cysteine peptidase
  • Zebrafish(553634) caspase 7, apoptosis-related cysteine peptidase
  • chicken(423901) caspase 7, apoptosis-related cysteine peptidase
  • naked mole-rat(101709568) caspase 7, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715159) caspase 7, apoptosis-related cysteine peptidase
  • cow(526279) caspase 7, apoptosis-related cysteine peptidase
  • sheep(101122741) caspase 7, apoptosis-related cysteine peptidase
  • domestic cat(768262) caspase 7, apoptosis-related cysteine peptidase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Caspase-7 Antibody, clone 1E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
N-Acetyl-Asp-Glu-Val-Asp-al, ≥95%, powder,
Especie
human
NSCI, ≥97% (HPLC), solid,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CASP7,
Especie
human