CAMLG
calcium modulating ligand
Sinónimos:
CAML
Especie:
Human CAMLG (819), Rat Camlg (81715), naked mole-rat Camlg (101712651), sheep CAMLG (101119046), domestic cat CAMLG (101100691), cow CAMLG (615658), Zebrafish camlg (404622), chicken CAMLG (395808), domestic guinea pig Camlg (100730375), dog CAMLG (474684)
ID UniProtKB:
ID del gen:
- Human(819) Summary: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
- Rat(81715) calcium modulating ligand
- naked mole-rat(101712651) calcium modulating ligand
- sheep(101119046) calcium modulating ligand
- domestic cat(101100691) calcium modulating ligand
- cow(615658) calcium modulating ligand
- Zebrafish(404622) calcium modulating ligand
- chicken(395808) calcium modulating ligand
- domestic guinea pig(100730375) calcium modulating ligand
- dog(474684) calcium modulating ligand
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