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Merck

CACNA1F

calcium channel, voltage-dependent, L type, alpha 1F subunit

Sinónimos:
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
Especie:
ID UniProtKB:
ID del gen:
  • Human(778) Summary: This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq, Feb 2012]
  • Mouse(54652) calcium channel, voltage-dependent, alpha 1F subunit
  • Rat(114493) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • sheep(101104552) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • naked mole-rat(101722090) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic guinea pig(100720484) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • Zebrafish(386662) calcium channel, voltage-dependent, alpha 1F subunit
  • domestic cat(101080870) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • dog(480915) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • cow(509779) calcium channel, voltage-dependent, L type, alpha 1F subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Blocker

Número de producto
Descripción
Especie
Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Amlodipine besylate, ≥98% (HPLC),
Especie
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Amlodipine besylate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
(±)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CACNA1F,
Especie
human