C8B
complement component 8, beta polypeptide
Sinónimos:
C82
Especie:
Human C8B (732), Mouse C8b (110382), Rat C8b (313421), chicken C8B (424669), Zebrafish c8b (793127), Horse C8B (100059423), domestic cat C8B (101099229), dog C8B (479555), Domestic Rabbit C8B (100009385), sheep C8B (101102522) ...Más
ID UniProtKB:
ID del gen:
- Human(732) Summary: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
- Mouse(110382) complement component 8, beta polypeptide
- Rat(313421) complement component 8, beta polypeptide
- chicken(424669) complement component 8, beta polypeptide
- Zebrafish(793127) complement component 8, beta polypeptide
- Horse(100059423) complement component 8, beta polypeptide
- domestic cat(101099229) complement component 8, beta polypeptide
- dog(479555) complement component 8, beta polypeptide
- Domestic Rabbit(100009385) complement component 8, beta polypeptide
- sheep(101102522) complement component 8, beta polypeptide
- cow(513217) complement component 8, beta polypeptide
- naked mole-rat(101696501) complement component 8, beta polypeptide
- domestic guinea pig(100729610) complement component 8, beta polypeptide
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