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Merck

BRD2

bromodomain containing 2

Sinónimos:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Especie:
ID UniProtKB:
ID del gen:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
Anti-Brd2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
I-BET762, ≥98% (HPLC),
Especie
human
OTX015, ≥98% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Brd2,
Especie
mouse
MISSION® esiRNA, targeting human BRD2,
Especie
human