BRAF
v-raf murine sarcoma viral oncogene homolog B
Sinónimos:
B-RAF1, BRAF1, NS7, RAFB1
Especie:
Human BRAF (673), Mouse Braf (109880), Rat Braf (114486), Horse BRAF (100065760), Zebrafish braf (403065), naked mole-rat Braf (101702762), chicken BRAF (396239), domestic guinea pig Braf (100717765), dog BRAF (475526), domestic cat BRAF (101092346) ...Más
ID UniProtKB:
ID del gen:
- Human(673) Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109880) Braf transforming gene
- Rat(114486) v-raf murine sarcoma viral oncogene homolog B
- Horse(100065760) v-raf murine sarcoma viral oncogene homolog B1
- Zebrafish(403065) v-raf murine sarcoma viral oncogene homolog B1
- naked mole-rat(101702762) v-raf murine sarcoma viral oncogene homolog B1
- chicken(396239) v-raf murine sarcoma viral oncogene homolog B1
- domestic guinea pig(100717765) v-raf murine sarcoma viral oncogene homolog B1
- dog(475526) v-raf murine sarcoma viral oncogene homolog B1
- domestic cat(101092346) v-raf murine sarcoma viral oncogene homolog B1
- cow(536051) v-raf murine sarcoma viral oncogene homolog B
- sheep(101107438) v-raf murine sarcoma viral oncogene homolog B1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-B-Raf Antibody, clone 2D3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
avian, bovine, feline, fish, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Phospho-B-Raf-T401 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-B-Raf Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot