BBC3
BCL2 binding component 3
Sinónimos:
JFY-1, JFY1, PUMA
Especie:
Human BBC3 (27113), Mouse Bbc3 (170770), Rat Bbc3 (317673), dog BBC3 (612153), Zebrafish bbc3 (751763), domestic guinea pig Bbc3 (101788977), naked mole-rat Bbc3 (101714844), cow BBC3 (782359)
ID UniProtKB:
ID del gen:
- Human(27113) Summary: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
- Mouse(170770) BCL2 binding component 3
- Rat(317673) Bcl-2 binding component 3
- dog(612153) BCL2 binding component 3
- Zebrafish(751763) BCL2 binding component 3
- domestic guinea pig(101788977) BCL2 binding component 3
- naked mole-rat(101714844) BCL2 binding component 3
- cow(782359) BCL2 binding component 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PUMA antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Puma BH3 domain Antibody, from rabbit,
Reactividad de especies
mouse
Aplicación
western blot