B4GALT4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
Sinónimos:
B4Gal-T4, beta4Gal-T4
Especie:
Human B4GALT4 (8702), Mouse B4galt4 (56375), Rat B4galt4 (303923), domestic guinea pig B4galt4 (100735550), dog B4GALT4 (608143), naked mole-rat B4galt4 (101723638), domestic cat B4GALT4 (101100325), cow B4GALT4 (511328), sheep B4GALT4 (101104949), Zebrafish b4galt4 (492760)
ID UniProtKB:
ID del gen:
- Human(8702) Summary: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(56375) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
- Rat(303923) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
- domestic guinea pig(100735550) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- dog(608143) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- naked mole-rat(101723638) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- domestic cat(101100325) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- cow(511328) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- sheep(101104949) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- Zebrafish(492760) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
- chicken(418341) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
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