ATRX
alpha thalassemia/mental retardation syndrome X-linked
Sinónimos:
ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX
Especie:
Human ATRX (546), Mouse Atrx (22589), Rat Atrx (246284), cow ATRX (514473), dog ATRX (480963), Domestic Rabbit ATRX (100358645), sheep ATRX (101117394), Zebrafish atrx (323299), Thale Cress ATRX (837382), naked mole-rat Atrx (101705766) ...Más
ID UniProtKB:
ID del gen:
- Human(546) Summary: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(22589) alpha thalassemia/mental retardation syndrome X-linked homolog (human)
- Rat(246284) alpha thalassemia/mental retardation syndrome X-linked
- cow(514473) alpha thalassemia/mental retardation syndrome X-linked
- dog(480963) alpha thalassemia/mental retardation syndrome X-linked
- Domestic Rabbit(100358645) alpha thalassemia/mental retardation syndrome X-linked
- sheep(101117394) alpha thalassemia/mental retardation syndrome X-linked
- Zebrafish(323299) alpha thalassemia/mental retardation syndrome X-linked homolog (human)
- Thale Cress(837382) ATRX, DEXDc and helicase domain-containing protein
- naked mole-rat(101705766) alpha thalassemia/mental retardation syndrome X-linked
- chicken(422331) alpha thalassemia/mental retardation syndrome X-linked
- domestic cat(101086543) alpha thalassemia/mental retardation syndrome X-linked
- domestic guinea pig(100715238) alpha thalassemia/mental retardation syndrome X-linked
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATRX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ATRX Antibody, clone 39f, clone 39F, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
western blot
western blot
Anti-ATRX Antibody, clone 23C, clone 23C, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
western blot
western blot
Anti-ATRX Antibody, clone 2A12, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot