ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
Sinónimos:
PMCA1, PMCA1kb
Especie:
Human ATP2B1 (490), Mouse Atp2b1 (67972), Rat Atp2b1 (29598), naked mole-rat Atp2b1 (101725886), domestic guinea pig Atp2b1 (100337638), dog ATP2B1 (403480), cow ATP2B1 (282641), domestic cat ATP2B1 (101098392), Domestic Rabbit ATP2B1 (100009543), Horse ATP2B1 (100051636) ...Más
ID UniProtKB:
ID del gen:
- Human(490) Summary: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(67972) ATPase, Ca++ transporting, plasma membrane 1
- Rat(29598) ATPase, Ca++ transporting, plasma membrane 1
- naked mole-rat(101725886) ATPase, Ca++ transporting, plasma membrane 1
- domestic guinea pig(100337638) ATPase, Ca++ transporting, plasma membrane 1
- dog(403480) ATPase, Ca++ transporting, plasma membrane 1
- cow(282641) ATPase, Ca++ transporting, plasma membrane 1
- domestic cat(101098392) ATPase, Ca++ transporting, plasma membrane 1
- Domestic Rabbit(100009543) ATPase, Ca++ transporting, plasma membrane 1
- Horse(100051636) ATPase, Ca++ transporting, plasma membrane 1
- sheep(101111268) ATPase, Ca++ transporting, plasma membrane 1
- chicken(374244) ATPase, Ca++ transporting, plasma membrane 1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-pan-PMCA Antibody, clone 5F10, clone 5F10, from mouse,
Reactividad de especies
chicken, human, rat
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot