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Merck

ATP1A2

ATPase, Na+/K+ transporting, alpha 2 polypeptide

Sinónimos:
FHM2, MHP2
Especie:
ID UniProtKB:
ID del gen:
  • Human(477) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
  • Mouse(98660) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Rat(24212) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Horse(100058251) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • chicken(396468) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • dog(488636) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • domestic guinea pig(100729524) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • naked mole-rat(101721770) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • cow(515161) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • sheep(101118148) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Domestic Rabbit(100008756) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • domestic cat(101096785) ATPase, Na+/K+ transporting, alpha 2 polypeptide

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Na+K+ ATPase α-2 Antibody, serum, Upstate®,
Reactividad de especies
rat
Aplicación
western blot
Anti-ATP1A2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Sodium Pump Subunit alpha-2 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse, porcine, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Digitoxin, ≥92% (HPLC), powder,
Especie
human
Digoxin, analytical standard,
Especie
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ATP1A2,
Especie
human