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Merck

ATF4

activating transcription factor 4

Sinónimos:
CREB-2, CREB2, TAXREB67, TXREB
Especie:
ID UniProtKB:
ID del gen:
  • Human(468) Summary: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
  • Mouse(11911) activating transcription factor 4
  • Rat(79255) activating transcription factor 4
  • naked mole-rat(101724287) activating transcription factor 4
  • domestic cat(101084297) activating transcription factor 4 (tax-responsive enhancer element B67)
  • sheep(100216465) activating transcription factor 4 (tax-responsive enhancer element B67)
  • domestic guinea pig(100732296) activating transcription factor 4
  • cow(509107) activating transcription factor 4 (tax-responsive enhancer element B67)
  • dog(474503) activating transcription factor 4 (tax-responsive enhancer element B67)
  • chicken(395693) activating transcription factor 4 (tax-responsive enhancer element B67)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATF4 Antibody, clone 1B21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

western blot
Anti-ATF4 Antibody, serum, from rabbit,
Reactividad de especies
human
Aplicación
ChIP
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ATF4,
Especie
human
MISSION® esiRNA, targeting mouse Atf4,
Especie
mouse