ASL
argininosuccinate lyase
Sinónimos:
ASAL
Especie:
Human ASL (435), Mouse Asl (109900), Rat Asl (59085), Zebrafish asl (393423), fruit fly asl (40682), dog ASL (479704), Horse ASL (100060801), Goat ASL (100860854), cow ASL (512771), naked mole-rat Asl (101709923)
ID UniProtKB:
ID del gen:
- Human(435) Summary: This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(109900) argininosuccinate lyase
- Rat(59085) argininosuccinate lyase
- Zebrafish(393423) argininosuccinate lyase
- fruit fly(40682) asterless
- dog(479704) argininosuccinate lyase
- Horse(100060801) argininosuccinate lyase
- Goat(100860854) argininosuccinate lyase
- cow(512771) argininosuccinate lyase
- naked mole-rat(101709923) argininosuccinate lyase
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