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Merck

ASGR1

asialoglycoprotein receptor 1

Sinónimos:
ASGPR, ASGPR1, CLEC4H1, HL-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(432) Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(11889) asialoglycoprotein receptor 1
  • Rat(24210) asialoglycoprotein receptor 1
  • sheep(101116157) asialoglycoprotein receptor 1
  • naked mole-rat(101707146) asialoglycoprotein receptor 1
  • domestic guinea pig(100714188) asialoglycoprotein receptor 1
  • cow(509121) asialoglycoprotein receptor 1
  • dog(489461) asialoglycoprotein receptor 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ASGR1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, guinea pig, horse, human, mouse, pig, rat, yeast
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Asgr1,
Especie
mouse
MISSION® esiRNA, targeting human ASGR1,
Especie
human