ARID1A
AT rich interactive domain 1A (SWI-like)
Sinónimos:
B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1
Especie:
Human ARID1A (8289), Mouse Arid1a (93760), Rat Arid1a (297867), sheep ARID1A (101115263), cow ARID1A (540181), domestic cat ARID1A (101086737), naked mole-rat Arid1a (101715459), dog ARID1A (487352), domestic guinea pig Arid1a (100714305), chicken ARID1A (419542)
ID UniProtKB:
ID del gen:
- Human(8289) Summary: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(93760) AT rich interactive domain 1A (SWI-like)
- Rat(297867) AT rich interactive domain 1A (SWI-like)
- sheep(101115263) AT rich interactive domain 1A (SWI-like)
- cow(540181) AT rich interactive domain 1A (SWI-like)
- domestic cat(101086737) AT rich interactive domain 1A (SWI-like)
- naked mole-rat(101715459) AT rich interactive domain 1A (SWI-like)
- dog(487352) AT rich interactive domain 1A (SWI-like)
- domestic guinea pig(100714305) AT rich interactive domain 1A (SWI-like)
- chicken(419542) AT rich interactive domain 1A (SWI-like)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BAF250a/ARID1a Antibody, clone PSG3, clone PSG3, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Anti-ARID1A Antibody, clone 1C3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-ARID1A Antibody, clone 9D4J6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot