APOE
apolipoprotein E
Sinónimos:
AD2, LDLCQ5, LPG
Especie:
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
ID UniProtKB:
ID del gen:
- Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
- Mouse(11816) apolipoprotein E
- Rat(25728) apolipoprotein E
- naked mole-rat(101717206) apolipoprotein E
- domestic guinea pig(100731633) apolipoprotein E
- cow(281004) apolipoprotein E
- Domestic Rabbit(100009337) apolipoprotein E
- dog(476438) apolipoprotein E
- domestic cat(101086769) apolipoprotein E
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat, zebrafish
Aplicación
immunohistochemistry
western blot
western blot
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
western blot
Anti-Apolipoprotein E4 (ApoE4) Antibody, clone 4E4, clone 4E4, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Apolipoprotein E Mouse mAb (E6D7), liquid, clone E6D7, Calbiochem®,
Reactividad de especies
human
Aplicación
Anti-ApoE4 Fragment nApoECF Antibody (Asp172), from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
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Descripción
Especie
esiRNA
Referencia del producto
Descripción
Especie