APAF1
apoptotic peptidase activating factor 1
Sinónimos:
APAF-1, CED4
Especie:
Human APAF1 (317), Mouse Apaf1 (11783), Rat Apaf1 (78963), dog APAF1 (482620), naked mole-rat Apaf1 (101706721), Horse APAF1 (100052552), cow APAF1 (537782), sheep APAF1 (100135699), domestic guinea pig Apaf1 (100719903), Zebrafish apaf1 (58131) ...Más
ID UniProtKB:
ID del gen:
- Human(317) Summary: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(11783) apoptotic peptidase activating factor 1
- Rat(78963) apoptotic peptidase activating factor 1
- dog(482620) apoptotic peptidase activating factor 1
- naked mole-rat(101706721) apoptotic peptidase activating factor 1
- Horse(100052552) apoptotic peptidase activating factor 1
- cow(537782) apoptotic peptidase activating factor 1
- sheep(100135699) apoptotic peptidase activating factor 1
- domestic guinea pig(100719903) apoptotic peptidase activating factor 1
- Zebrafish(58131) apoptotic protease activating factor 1
- chicken(417926) apoptotic peptidase activating factor 1
- domestic cat(768257) apoptotic peptidase activating factor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Apaf-1 Antibody, NT, Chemicon®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-Apaf-1 Antibody, clone 1C7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, monkey
Aplicación
ELISA
affinity binding assay
immunocytochemistry
western blot
affinity binding assay
immunocytochemistry
western blot
Anti-Apaf-1 Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Apaf-1 Antibody, clone 13F11, clone 13F11, from rat,
Reactividad de especies
mouse, rat
Aplicación
western blot