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Merck

ALDH1A2

aldehyde dehydrogenase 1 family, member A2

Sinónimos:
RALDH(II), RALDH2, RALDH2-T
Especie:
ID UniProtKB:
ID del gen:
  • Human(8854) Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
  • Mouse(19378) aldehyde dehydrogenase family 1, subfamily A2
  • Rat(116676) aldehyde dehydrogenase 1 family, member A2
  • naked mole-rat(101699741) aldehyde dehydrogenase 1 family, member A2
  • domestic guinea pig(100718164) aldehyde dehydrogenase 1 family, member A2
  • dog(478319) aldehyde dehydrogenase 1 family, member A2
  • sheep(101117509) aldehyde dehydrogenase 1 family, member A2
  • chicken(395844) aldehyde dehydrogenase 1 family, member A2
  • Zebrafish(116713) aldehyde dehydrogenase 1 family, member A2
  • Domestic Rabbit(100339014) aldehyde dehydrogenase 1 family, member A2
  • domestic cat(101082916) aldehyde dehydrogenase 1 family, member A2
  • cow(535075) aldehyde dehydrogenase 1 family, member A2
  • Horse(100054550) aldehyde dehydrogenase 1 family, member A2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ALDH1A2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-RalDH2 (ALDH1A2), from rabbit, purified by affinity chromatography,
Reactividad de especies
canine, human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
4-Hydroxycoumarin, 98%,
Especie
rat, mouse
Puerarin, ≥98.0% (HPLC),
Especie
mouse
6,7-Dimethoxycoumarin, 98%,
Especie
rat, mouse
7-Hydroxyflavanone, 98%,
Especie
rat, mouse
Ononin, ≥99.0% (TLC),
Especie
rat, mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ALDH1A2,
Especie
human
MISSION® esiRNA, targeting mouse Aldh1a2,
Especie
mouse