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Merck

AKT3

v-akt murine thymoma viral oncogene homolog 3

Sinónimos:
MPPH, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(10000) Summary: The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(23797) thymoma viral proto-oncogene 3
  • Rat(29414) v-akt murine thymoma viral oncogene homolog 3
  • domestic guinea pig(100724315) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Zebrafish(100149794) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • chicken(421497) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • dog(442964) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • domestic cat(101092818) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • cow(100137872) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Horse(100054961) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Domestic Rabbit(100353706) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • sheep(101118462) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • naked mole-rat(101701289) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Akt3/PKBγ Antibody, clone GMA104, clone GMA104, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
Anti-Akt3/PKBγ Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
Anti-Phospho-Akt-S473 antibody produced in rabbit, ,
Reactividad de especies
human, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
GSK690693, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
SILuLite AKT3, RAC-gamma serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Especie
human
Akt3/PKBγ (S472D) Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant human Akt3/PKBγ, amino acids 117-end, containing a S472D mutation. For use in Kinase Assays.,
Especie
human
SILuProt AKT3, RAC-gamma serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human AKT3,
Especie
human
MISSION® esiRNA, targeting mouse Akt3,
Especie
mouse

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
STK Substrate 2, STK Substrate 2 primarily used in Kinase Assays.,
Especie
human