AKAP13
A kinase (PRKA) anchor protein 13
Sinónimos:
AKAP-13, AKAP-Lbc, ARHGEF13, BRX, HA-3, Ht31, LBC, PRKA13, PROTO-LB, PROTO-LBC, c-lbc, p47
Especie:
Human AKAP13 (11214), Mouse Akap13 (75547), Rat Akap13 (293024), cow AKAP13 (504288), Horse AKAP13 (100070242), Domestic Rabbit AKAP13 (100342409), sheep AKAP13 (101115486), domestic guinea pig Akap13 (100733906), naked mole-rat Akap13 (101720563), Zebrafish akap13 (557441) ...Más
ID UniProtKB:
ID del gen:
- Human(11214) Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
- Mouse(75547) A kinase (PRKA) anchor protein 13
- Rat(293024) A kinase (PRKA) anchor protein 13
- cow(504288) A kinase (PRKA) anchor protein 13
- Horse(100070242) A kinase (PRKA) anchor protein 13
- Domestic Rabbit(100342409) A kinase (PRKA) anchor protein 13
- sheep(101115486) A kinase (PRKA) anchor protein 13
- domestic guinea pig(100733906) A kinase (PRKA) anchor protein 13
- naked mole-rat(101720563) A kinase (PRKA) anchor protein 13
- Zebrafish(557441) A kinase (PRKA) anchor protein 13
- chicken(415502) A kinase (PRKA) anchor protein 13
- domestic cat(101093021) A kinase (PRKA) anchor protein 13
- dog(479032) A kinase (PRKA) anchor protein 13
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
