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Merck

ACTN2

actinin, alpha 2

Sinónimos:
CMD1AA
Especie:
ID UniProtKB:
ID del gen:
  • Human(88) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
  • Mouse(11472) actinin alpha 2
  • Rat(291245) actinin alpha 2
  • naked mole-rat(101721630) actinin, alpha 2
  • domestic guinea pig(100712846) actinin, alpha 2
  • chicken(396263) actinin, alpha 2
  • Zebrafish(641575) actinin, alpha 2
  • domestic cat(101101415) actinin, alpha 2
  • dog(479191) actinin, alpha 2
  • cow(536607) actinin, alpha 2
  • Horse(100033870) actinin, alpha 2
  • Domestic Rabbit(100350274) actinin, alpha 2
  • sheep(101116372) actinin, alpha 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ACTN2 Antibody, clone 2P7E6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Anti-α-actinina (sarcomérica) monoclonal antibody produced in mouse, clone EA-53, ascites fluid,
Reactividad de especies
bovine, canine, chicken, feline, fish, frog, goat, hamster, human, lizard, mouse, pig, rabbit, rat, sheep, snake
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ACTN2,
Especie
human
MISSION® esiRNA, targeting mouse Actn2,
Especie
mouse