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Merck

ACACA

acetyl-CoA carboxylase alpha

Sinónimos:
ACAC, ACACAD, ACC, ACC1, ACCA
Especie:
ID UniProtKB:
ID del gen:
  • Human(31) Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(107476) acetyl-Coenzyme A carboxylase alpha
  • Rat(60581) acetyl-CoA carboxylase alpha
  • dog(491130) acetyl-CoA carboxylase alpha
  • chicken(396504) acetyl-CoA carboxylase alpha
  • Zebrafish(559403) acetyl-Coenzyme A carboxylase alpha
  • cow(281590) acetyl-CoA carboxylase alpha
  • Horse(100071472) acetyl-CoA carboxylase alpha
  • domestic cat(101083046) acetyl-CoA carboxylase alpha
  • Domestic Rabbit(100355970) acetyl-CoA carboxylase alpha
  • Goat(100861224) acetyl-CoA carboxylase alpha
  • sheep(443186) acetyl-CoA carboxylase alpha
  • naked mole-rat(101706028) acetyl-CoA carboxylase alpha
  • domestic guinea pig(100733410) acetyl-CoA carboxylase alpha

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-fosfo-acetil-CoA carboxilasa (Ser79), Upstate®, from rabbit,
Reactividad de especies
bovine, canine, chicken, dog, human, mouse, rat
Aplicación
western blot
Anti-Acetyl CoA Carboxylase 1, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-phospho-Acetyl CoA Carboxylase (Ser79) Antibody, clone BK102, clone BK102, Upstate®, from mouse,
Reactividad de especies
mouse, rat
Aplicación
western blot
Anti-Acetyl CoA Carboxylase 1 Antibody, clone 10H2.1, clone 10H2.1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-acetyl CoA Carboxylase Antibody, clone 7D2.2, clone 7D2.2, from mouse,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ACACA (1),
Especie
human
MISSION® esiRNA, targeting mouse Acaca,
Especie
mouse
MISSION® esiRNA, targeting human ACACA (2),
Especie
human