ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
Sinónimos:
ABC7, ASAT, Atm1p, EST140535
Especie:
Human ABCB7 (22), Mouse Abcb7 (11306), Rat Abcb7 (302395), domestic cat ABCB7 (101082805), Horse ABCB7 (100060544), dog ABCB7 (491967), chicken ABCB7 (422326), fruit fly ABCB7 (38193), Zebrafish abcb7 (566515), naked mole-rat Abcb7 (101721701) ...Más
ID UniProtKB:
ID del gen:
- Human(22) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
- Mouse(11306) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- Rat(302395) ATP-binding cassette, subfamily B (MDR/TAP), member 7
- domestic cat(101082805) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- Horse(100060544) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- dog(491967) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- chicken(422326) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- fruit fly(38193) CG7955 gene product from transcript CG7955-RA
- Zebrafish(566515) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- naked mole-rat(101721701) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- domestic guinea pig(100724759) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- Domestic Rabbit(100351866) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- sheep(101113989) ATP-binding cassette, sub-family B (MDR/TAP), member 7
- cow(533669) ATP-binding cassette, sub-family B (MDR/TAP), member 7
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