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Merck

ABCA1

ATP-binding cassette, sub-family A (ABC1), member 1

Sinónimos:
ABC-1, ABC1, CERP, HDLDT1, TGD
Especie:
Human ABCA1 (19), Mouse Abca1 (11303), Rat Abca1 (313210), chicken ABCA1 (373945), cow ABCA1 (535379), sheep ABCA1 (101119015), domestic cat ABCA1 (101083885), Horse ABCA1 (100054241), dog ABCA1 (481651), Thale Cress ABCA1 (818768) ...Más
ID UniProtKB:
O95477, Q5VX33, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08
ID del gen:
  • Human(19) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
  • Mouse(11303) ATP-binding cassette, sub-family A (ABC1), member 1
  • Rat(313210) ATP-binding cassette, subfamily A (ABC1), member 1
  • chicken(373945) ATP-binding cassette, sub-family A (ABC1), member 1
  • cow(535379) ATP-binding cassette, sub-family A (ABC1), member 1
  • sheep(101119015) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic cat(101083885) ATP-binding cassette, sub-family A (ABC1), member 1
  • Horse(100054241) ATP-binding cassette, sub-family A (ABC1), member 1
  • dog(481651) ATP-binding cassette, sub-family A (ABC1), member 1
  • Thale Cress(818768) ABC transporter A family member 1
  • naked mole-rat(101704546) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic guinea pig(100720792) ATP-binding cassette, sub-family A (ABC1), member 1
  • Domestic Rabbit(100356765) ATP-binding cassette, sub-family A (ABC1), member 1

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
T2320
T0901317, ≥98%,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MAB10005
Anti-ABCA1 Antibody, clone AB.H10, clone AB.H10, Chemicon®, from mouse,
Reactividad de especies
chicken, human, mouse
Aplicación
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
MABN893
Anti-ABCA1 Antibody, clone MABI98-7, clone MAB198-7, from rat,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
ZRB2057
Anti-ABCA1 Antibody, clone 1J11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
1563309
Probucol, United States Pharmacopeia (USP) Reference Standard,
Especie
human
P9672
Probucol, analytical standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU068891
MISSION® esiRNA, targeting mouse Abca1,
Especie
mouse