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Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking

Dehydrogenation through Cooperative Base Metal Catalysis

The Sorensen group has reported a dual-catalytic system capable of dehydrogenating alkanes & alcohols at low temperatures with hydrogen gas as the sole byproduct

Buchwald Ligands

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Designing Peptides

This summary highlights some important points that should be considered in the design of a peptide. If you would like help with peptide design, our technical support department can assist you

Retinoic Acid and Gene Expression

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.

Petroleum Hydrocarbon Standards for SIMDIS Analyses

Understanding the boiling point range distribution of petrochemical products is critical for selection of the proper method to process feed stocks, for process control, for contaminant identification and for development of new test methods.

Proline Derivatives and Analogs

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Click Chemistry in Drug Discovery

Drug discovery process by utilizing chemistry reaction of Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of terminal alkynes with organoazides to yield 1,4-disubstituted 1,2,3-triazoles.

Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform

Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.

Dendrons and Hyperbranched Polymers: Multifunctional Tools for Materials Chemistry

Dendrons in nanomaterials - Find features and benefits of polyester dendrons and hyperbranched polymer products.

Mesoporous Materials: Properties and Applications

Mesoporous Materials include a range of high surface area porous silicates with applications in gas adsorption, drug delivery, diagnostics and catalysis.

Controlled Fabrication Methods for Tissue Engineering Constructs

Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

The Application of Quantum Dots in Display Technology

Quantum Dots (QDs), a nanoscale material with unique optical properties governed by quantum mechanics, have been incorporated into a new display technology under development at QD Vision, Inc.

Biomedical Implant Devices Fabricated from Low Young’s Modulus Titanium Alloys Demonstrating High Mechanical Biocompatibility

Biomedical implants are essentially foreign substances within the human body that must survive many years’ exposure to demanding mechanical and physiological conditions. Despite these challenges, metal implants have been widely used to substitute for or rebuild hard tissues such as

Mgat4 May Play a Role in Increased Sialylation by Overexpressing Functional MGAT1 in Mgat1-Disrupted Chinese Hamster Ovary (CHO) Cells

MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.

How Transfection Works

This brief webinar provides an overview of what transfection is and the methods that are used to introduce DNA or RNA into eukaryotic cells.

Methods Used to Detect Proteins and Nucleic Acids Bound to Membranes

Background and protocols describing the various methods used by molecular biologists to detect samples of protein or nucleic acids bound to membranes.

Cloning & Expression Vectors

Expression Vectors for Bacterial, Mammalian and Insect Cell Systems. Featured are a variety of tags, promoters and elements for secretion, transient, stable and bicistronic expression.

p53: DNA Damage Response and Cancer

p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.

Definitions and Genotypes of e-coli

Genotypes of Selected E. coli strains in molecular biology

Universal (Switchable) RAFT Agents for Well-Defined Block Copolymers

Universal (Switchable) RAFT agents allow for the polymerization of both less activated and more activated monomers and are ideal for the synthesis of well-defined block copolymers.

Click Chemistry in Biomaterials Science

"Click" Chemistry in (Bio)Materials Science

Digoxigenin (DIG) Labeling Methods

Digoxigenin (DIG) labeling methods and kits for DNA and RNA DIG probes, random primed DNA labeling, nick translation labeling, 5’ and 3’ oligonucleotide end-labeling.

Nucleic Acid Modifying Enzyme Selection Chart (Ultra Pure)

A helpful chart for selection of correct nucleic acid modifying enzyme.

Transforming E.coli with Engineered Plasmid

Making Competent Cells; Making Agar Plates; Bacterial Transformation; Picking Colonies; Growing Bacteria in Liquid Culture; Freezing Bacteria.

PCR/qPCR Data Analysis

After a traditional PCR has been completed, the PCR/qPCR data analysis is conducted by resolution through an agarose gel or, more recently, through a capillary.

Designing Temperature and pH Sensitive NIPAM Based Polymers

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

ChIC and CUT&RUN Data Analysis Tool Overview

Chromatin Immunocleavage (ChIC) and CUT&RUN data analysis tool for file management and downstream sequencing data analyses.

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