Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells.

Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells.

Experimental and therapeutic medicine (2014-10-08)

Xue DU, Yongmei Li, Xu Jing, Lina Zhao

ABSTRACT

The aim of the present study was to investigate the effect of heat shock protein 90 (Hsp90)-specific inhibitor geldanamycin (GA) on the proliferation and apoptosis induced by vascular endothelial growth factor-C (VEGF-C) in cervical cancer cells. HeLa cells (1×10

MATERIALS

Product Number

Brand

Product Description

SRP3184

Sigma-Aldrich

VEGF-C human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

SRP4633

Sigma-Aldrich

VEGF-C human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

P215

Sigma-Aldrich

PD 98,059, solid