- Cytotoxicity of captafol in mammalian cells.
Cytotoxicity of captafol in mammalian cells.
Biomedical and environmental sciences : BES (1994-09-01)
M A Rodrigues, M D'Angelo
PMID7531451
ABSTRACT
The cytotoxicity of captafol, a phthalimide-derived fungicide, was evaluated in IB-RS-2 cells. Captafol at 0.12-1.0 microgram/ml blocks the cell multiplication. This effect is concentration-dependent, only partially reversible and the degree of inhibition increases with time. The synthesis of DNA and RNA is inhibited in parallel by increasing concentrations of the chemical.