- A flexible route to (5R)-thiolactomycin, a naturally occurring inhibitor of fatty acid synthesis.
A flexible route to (5R)-thiolactomycin, a naturally occurring inhibitor of fatty acid synthesis.
Organic letters (2003-02-26)
Jill M McFadden, Gojeb L Frehywot, Craig A Townsend
PMID12599477
ABSTRACT
[formula: see text] A new and efficient asymmetric synthesis of naturally occurring (5R)-thiolactomycin (1) using D-alanine as the source of chirality is described.
MATERIALS