WDFY3
WD repeat and FYVE domain containing 3
Synonyms:
ALFY, ZFYVE25
Species:
Human WDFY3 (23001), Mouse Wdfy3 (72145), Rat Wdfy3 (305164), sheep WDFY3 (101110676), Horse WDFY3 (100052494), cow WDFY3 (537096), domestic cat WDFY3 (101081888), dog WDFY3 (487841), chicken WDFY3 (422613), Zebrafish wdfy3 (568432) ...More
UniProtKB ID:
Gene ID:
- Human(23001) Summary: This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
- Mouse(72145) WD repeat and FYVE domain containing 3
- Rat(305164) WD repeat and FYVE domain containing 3
- sheep(101110676) WD repeat and FYVE domain containing 3
- Horse(100052494) WD repeat and FYVE domain containing 3
- cow(537096) WD repeat and FYVE domain containing 3
- domestic cat(101081888) WD repeat and FYVE domain containing 3
- dog(487841) WD repeat and FYVE domain containing 3
- chicken(422613) WD repeat and FYVE domain containing 3
- Zebrafish(568432) WD repeat and FYVE domain containing 3
- naked mole-rat(101702562) WD repeat and FYVE domain containing 3
- domestic guinea pig(100723266) WD repeat and FYVE domain containing 3
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