UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
Synonyms:
Species:
Human UGT2A1 (10941), Mouse Ugt2a1 (94215), Rat Ugt2a1 (63867), Zebrafish ugt2a1 (100006320), domestic guinea pig Ugt2a1 (100717542), naked mole-rat Ugt2a1 (101713955), sheep UGT2A1 (101119640)
UniProtKB ID:
Gene ID:
- Human(10941) Summary: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Mouse(94215) UDP glucuronosyltransferase 2 family, polypeptide A1
- Rat(63867) UDP glucuronosyltransferase 2 family, polypeptide A1
- Zebrafish(100006320) UDP glucuronosyltransferase 2 family, polypeptide A1
- domestic guinea pig(100717542) UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
- naked mole-rat(101713955) UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
- sheep(101119640) UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
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