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Merck

UGCG

UDP-glucose ceramide glucosyltransferase

Synonyms:
GCS, GLCT1
Species:
UniProtKB ID:
Gene ID:
  • Human(7357) Summary: Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
  • Mouse(22234) UDP-glucose ceramide glucosyltransferase
  • Rat(83626) UDP-glucose ceramide glucosyltransferase
  • chicken(427335) UDP-glucose ceramide glucosyltransferase
  • Zebrafish(553944) UDP-glucose ceramide glucosyltransferase
  • domestic cat(101101006) UDP-glucose ceramide glucosyltransferase
  • dog(481666) UDP-glucose ceramide glucosyltransferase
  • cow(514357) UDP-glucose ceramide glucosyltransferase
  • Horse(100057611) UDP-glucose ceramide glucosyltransferase
  • domestic guinea pig(100730880) UDP-glucose ceramide glucosyltransferase
  • sheep(101111687) UDP-glucose ceramide glucosyltransferase

Custom & Knockdown Gene Products

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Small Molecule - Inhibitor

Product Number
Description
Species
N-Butyldeoxynojirimycin, film (dried in situ),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human UGCG,
Species
human
MISSION® esiRNA, targeting mouse Ugcg,
Species
mouse