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Merck

UBR5

ubiquitin protein ligase E3 component n-recognin 5

Synonyms:
DD5, EDD, EDD1, HYD
Species:
Human UBR5 (51366), Mouse Ubr5 (70790), Rat Ubr5 (117060), domestic guinea pig Ubr5 (100720846), naked mole-rat Ubr5 (101719374), Zebrafish ubr5 (334627), chicken UBR5 (420252), dog UBR5 (475055), domestic cat UBR5 (101083741), cow UBR5 (515582)
UniProtKB ID:
O95071, B2RP24, O94970, Q9NPL3
Gene ID:
  • Human(51366) Summary: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(70790) ubiquitin protein ligase E3 component n-recognin 5
  • Rat(117060) ubiquitin protein ligase E3 component n-recognin 5
  • domestic guinea pig(100720846) ubiquitin protein ligase E3 component n-recognin 5
  • naked mole-rat(101719374) ubiquitin protein ligase E3 component n-recognin 5
  • Zebrafish(334627) ubiquitin protein ligase E3 component n-recognin 5
  • chicken(420252) ubiquitin protein ligase E3 component n-recognin 5
  • dog(475055) ubiquitin protein ligase E3 component n-recognin 5
  • domestic cat(101083741) ubiquitin protein ligase E3 component n-recognin 5
  • cow(515582) ubiquitin protein ligase E3 component n-recognin 5
  • sheep(101104323) ubiquitin protein ligase E3 component n-recognin 5

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
MABF1110
Anti-UBR5 Antibody, clone 16G10.1, clone 16G10.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
ABE2863M
Anti-E3 ubiquitin-protein ligase (UBR5/EDD), serum, from rabbit,
Species Reactivity
human, mouse
Application
immunofluorescence
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU047921
MISSION® esiRNA, targeting human UBR5,
Species
human
EMU084611
MISSION® esiRNA, targeting mouse Ubr5,
Species
mouse