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Merck

TUBA4A

tubulin, alpha 4a

Synonyms:
H2-ALPHA, TUBA1
Species:
UniProtKB ID:
Gene ID:
  • Human(7277) Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
  • Mouse(22145) tubulin, alpha 4A
  • Rat(316531) tubulin, alpha 4A
  • sheep(100302357) tubulin, alpha 4a
  • sheep(443104) tubulin, alpha 4a
  • naked mole-rat(101720265) tubulin, alpha 4a
  • domestic guinea pig(100734500) tubulin, alpha 4a
  • dog(478918) tubulin, alpha 4a
  • cow(777775) tubulin, alpha 4a
  • Horse(100059249) tubulin, alpha 4a
  • chicken(418166) tubulin, alpha 4a
  • domestic cat(101095277) tubulin, alpha 4a

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-α-Tubulin Antibody, clone 3P2D9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-α-Tubulin antibody produced in mouse, ascites fluid, clone B-5-1-2,
Species Reactivity
chlamydomonas, african green monkey, bovine, chicken, human, kangaroo rat, mouse, rat, sea urchin
Application
immunofluorescence
radioimmunoassay

western blot
Monoclonal Anti-Tubulin, Acetylated antibody produced in mouse, clone 6-11B-1, ascites fluid,
Species Reactivity
bovine, chicken, frog, hamster, human, invertebrates, monkey, mouse, pig, plant, protista, rat
Application
ELISA
dot blot

electron microscopy

immunocytochemistry

radioimmunoassay

western blot
Monoclonal Anti-α-Tubulin antibody produced in mouse, clone DM1A, ascites fluid,
Species Reactivity
amphibian, bovine, chicken, fungi, human, mouse, rat, yeast
Application
immunofluorescence
western blot
Anti-Acetylated Tubulin antibody, Mouse monoclonal, clone 6-11B-1, purified from hybridoma cell culture,
Species Reactivity
bovine, chicken, frog, hamster, human, invertebrates, monkey, mouse, pig, plant, rat
Application
dot blot
electron microscopy

immunohistochemistry

radioimmunoassay

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Colchicine, (European Pharmacopoeia (EP) Reference Standard),
Species
human
Paclitaxel, European Pharmacopoeia (EP) Reference Standard,
Species
human
Paclitaxel semi-synthetic for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Colchicine, phyproof® Reference Substance,
Species
human
Colchicine, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TUBA4A,
Species
human
MISSION® esiRNA, targeting mouse Tuba4a,
Species
mouse